A laudatio for Michel Serres might be based on the opportunity to go over again the stages of his thought, through the rich literary production and the masters whom his philosophical project is based on. The research - and in itself the passage from the natural sciences to the human sciences starts by considering the turning points of humanity toward the transcendental space of communication which characterizes Serres’ trans-disciplinary investigation. Scientific principles from Lucretius, Archimedes to Prigogines and information Theory get integrated with the anthropological philosophy that wants to find out the basis of the culture, the meaning of the artistic and literary creativity, till the hypothesis and the pedagogical proposal of the third instructed to reach the hominescence, a new rising of the human that in Serres becomes also a moral commitment of peace and love in these tragic and painful times.