This paper argues a critical reflection about the dynamics of the Sicilian Health System. The analysis of its internal reforms shows the effort to achieve a gradual decentralization of management and control bodies. It was conceptualized as a de-generalization process, described starting from the von Bertalanffy’s General Systems Theory. This latter allows to fit the concept of complexity to the social systems dynamic’s, characterized by specific rules and standards aimed to an ever new fitting to the environment.
Keywords: Health System, Sicilian region, General Systems Theory, complexity, de-generalization process, social systems dynamic’s.