Epileptic encephalopathies in the development age (West syndrome and Landau-Kleffner syndrome): an overview
Journal title CHILD DEVELOPMENT & DISABILITIES - SAGGI
Author/s Marta De Rinaldis, Leonarda Gennaro, Luciana Losito, Marilena Cacudi, Antonio Trabacca
Publishing Year 2012 Issue 2010/Suppl. 3
Language Italian Pages 23 P. 11-33 File size 160 KB
DOI 10.3280/CDD2010-S03002
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Object of the article are the West syndrome and the Landau-Kleffner syndrome, two clinical pictures which belong to the group of "epileptic encephalopathies", that according to the 2001 classification contribute to a progressive deterioration of the brain functions. The authors explore in depth the etiopathogenic, clinical, electroencephalographic and prognostic aspects of the two syndromes and confirm the role they play in causing cognitive damages and behavioral decline, stressing the importance of a timely and effective pharmacological intervention by controlling seizures and improving the growth outcome.
Keywords: West syndrome, Landau-Kleffner syndrome, epileptic encephalopathies, cognitive impairment, growth outcome
Marta De Rinaldis, Leonarda Gennaro, Luciana Losito, Marilena Cacudi, Antonio Trabacca, Le encefalopatie epilettiche in età evolutiva (sindrome di West e sindrome di Landau-Kleffner): una overview in "CHILD DEVELOPMENT & DISABILITIES - SAGGI" Suppl. 3/2010, pp 11-33, DOI: 10.3280/CDD2010-S03002