Neurosviluppo e vaccini: dall’epigenetica alla clinica

Titolo Rivista PNEI REVIEW
Autori/Curatori Cristina Panisi, Ernesto Burgio
Anno di pubblicazione 2018 Fascicolo 2018/1
Lingua Italiano Numero pagine 16 P. 76-91 Dimensione file 1136 KB
DOI 10.3280/PNEI2018-001007
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La ridotta percezione dell’utilità dei vaccini e il timore di effetti indesiderati hanno motivato la crescente titubanza nei confronti della vaccinoprofilassi negli ultimi anni. In particolare, la paura che i vaccini possano provocare autismo rappresenta il principale motivo di esitazione. Il tentativo di mettere sullo sfondo la paura dell’autismo mettendo in primo piano la paura delle malattie infettive appare una strategia poco efficace, poiché orienta la scelta sulla base dell’emotività e non della consapevolezza. Con l’intento di attenuare i timori dell’autismo attraverso una migliore conoscenza di questa condizione, verrà descritto il modello patogenetico che meglio rende conto delle modalità di insorgenza e delle caratteristiche cliniche dei disturbi dello spettro autistico. La presentazione porterà a concludere che un semplicistico modello tradizionale di causa-effetto non è in grado di giustificare le caratteristiche epidemiologiche e cliniche dell’autismo. Dunque, non la colpevolizzazione di un singolo fattore di rischio, bensì la consapevolezza della complessità del modello patogenetico, potrà orientare verso un efficace intervento di prevenzione primaria per i disturbi del neurosviluppo.;

Keywords:Vaccinazioni, Titubanza vaccinale, Disturbi del neurosviluppo, Epigenetica, Neuroinfiammazione, Prevenzione primaria.

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Cristina Panisi, Ernesto Burgio, Neurosviluppo e vaccini: dall’epigenetica alla clinica in "PNEI REVIEW" 1/2018, pp 76-91, DOI: 10.3280/PNEI2018-001007